Preparation of -pinene microcapsulation.
College of Life Sciences, Northeast Forestry University, Harbin, 150040, P. R. China.
Received Date:
December 31, 1899
Revised Date:
December 31, 1899
Published Date:
July 29, 2013
Abstract
An -pinene slow-release microcapsule with complex coacervation was prepared with chitosan and
Arabic gum as wall materials. The optimal preparation process condition was obtained by applying a
single-factor test and orthogonal experiment. The results showed that the concentrations of wall material
and Arabic gum were 0.2% and 3.5%, respectively, emulsifier content was 2.5%, ratio of core and
wall material was 1:1, reaction temperature was 45 c, pH was 4.5, time for coacervation was 60 min
and stirring revolutions 770 round/ min were the best preparation process conditions. Uniform spherical
microcapsules had an average particle size of 5 m. The encapsulation efficiency and drug loading were
up to (51.70 2.5)% and (42.11 2.3)%. The microcapsule can extend releasing time of 琢-pinene,
prolong its activity of time, thus expand its scope of application.
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