Abstract: To analyze the patterns of human disturbance in the wetland ecological system of Jiansanjiang plain, northeastern China, we measured the proportion of disturbance (pd) and its adjacency (pdd) of land cover using a moving window algorithm. The results show that the change of land use has a significant effect on the disturbance patterns at multiple scales from 2001 to 2006, and the cropland disturbance proportion reached 37.94%. The disturbance clusters 1 (C1) and 2 (C2) mainly occurred at water, forest and marsh region, with small values of disturbance. However, rice field and cropland accounted for 74% and 62% of the proportion of disturbance at the cluster C7 and C8, respectively, indicating cultivation is the main influence factor which disturbs the wetland ecological system at this region. Disturbance adjacency at multiple scales verifies that human disturbance occurred at certain scales. 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