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    包颖, 张国财. 单凝聚法制备豚草提取物微胶囊剂的研究[J]. 北京林业大学学报, 2013, 35(4): 101-105.
    引用本文: 包颖, 张国财. 单凝聚法制备豚草提取物微胶囊剂的研究[J]. 北京林业大学学报, 2013, 35(4): 101-105.
    BAO Ying, ZHANG Guo-cai.. Microcapsules with ragweed extraction by single coacervation.[J]. Journal of Beijing Forestry University, 2013, 35(4): 101-105.
    Citation: BAO Ying, ZHANG Guo-cai.. Microcapsules with ragweed extraction by single coacervation.[J]. Journal of Beijing Forestry University, 2013, 35(4): 101-105.

    单凝聚法制备豚草提取物微胶囊剂的研究

    Microcapsules with ragweed extraction by single coacervation.

    • 摘要: 利用外来入侵植物豚草的粗提物质为囊芯材料,以明胶为囊皮材料,采用单凝聚法制备豚草提取物微胶囊制 剂。结果表明:制成的微胶囊外部形态经电子扫描显微镜检测形态规则、完整;红外光谱分析显示囊芯材料包覆于 囊皮材料中;利用紫外分光光度仪测其微胶囊的效率和有效载量,分别是(44.79 ±1.36)% 和(59.72 ±1.81)%;利 用激光粒度分析仪测其粒径分布,得到中位径25.50 μm;热重分析结果可以看出,微胶囊的热稳定性优于囊芯物 质;因此制成的豚草提取物微胶囊剂弥补了植物源提取物质在稳定性上的缺陷,使其活性延长。

       

      Abstract: The extraction of exotic plant ragweed (Ambrosia artemisiifolia L. ) was made as core material and the gelatin was used as shell material to make the extraction into microcapsules by the single coacervation method. It can prevent the extraction of ragweed from inactivation, which could be easily caused by external condition such as illumination and temperature. The microcapsule technique can improve the property of extraction. The results showed that the morphology of microcapsules was regular and integrated observed under scanning electron microscope (SEM) . Moreover, the core material was coated with shell material observed by the infrared spectrum analysis with Fourier transform infrared spectroscopy (FTIR). The association efficiency and loading capacity of the microcapsules determined by ultraviolet spectrophotometer were (44.79 ±1.36)% and (59.72 ±1.81)%, respectively. The medium diameter was 25.50 μm analyzed with laser diffraction particle size analyzer. And the results of thermogravimetric analysis (TGA) demonstrated that the thermal stability of the microcapsules was superior to the core material. Consequently, the microcapsules with the extraction can avoid the unstable defect of the natural extraction. In addition, the activity was also lengthened by this technique

       

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